Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27364663 | 0.84 | IRAK4 (0.42) | MAPTBRAFCYP3A4AAK1 | |
| SCHEMBL28741615 | 0.78 | RIPK2 (0.41) | CA1CA2HSD11B1HTR1AHTR1D | |
| SCHEMBL27364477 | 0.76 | MAPT (0.37) | MAPTCA1CA2MAOBHSD11B1 | |
| SCHEMBL27364340 | 0.74 | ESR1 (0.56) | MAPTCYP3A4ROCK1AAK1 | |
| SCHEMBL30779360 | 0.72 | NCF1 (0.54) | MAPTCYP3A4 | |
| SCHEMBL30779359 | 0.72 | NCF1 (0.54) | MAPTCYP3A4 | |
| SCHEMBL1064633 | 0.70 | CA1 (0.50) | CA1CA2HSD11B1HTR1AHTR1D | |
| SCHEMBL3313661 | 0.70 | CA1 (0.43) | MAPTCA1CA2HSD11B1 | |
| SCHEMBL400021 | 0.70 | CA1 (0.44) | CA1CA2HSD11B1CYP3A4ACP1 | |
| SCHEMBL3317026 | 0.70 | CA1 (0.47) | CA1CA2HSD11B1HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049976-A1 | N-METHYL-4-(QUINOLIN-2-YL)PYRIDIN-2-AMINE COMPOUNDS | ABBVIE INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| WO-2024049976-A1 | N-METHYL-4-(QUINOLIN-2-YL)PYRIDIN-2-AMINE COMPOUNDS | ABBVIE INC. (US) | 2024-03-07 | — | — | WO | disclosed |