Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27364663 | 0.81 | IRAK4 (0.42) | MAPTAAK1 | |
| SCHEMBL27364359 | 0.76 | MAPT (0.47) | MAPTAAK1HSD11B1MAOBCA1 | |
| SCHEMBL17430156 | 0.72 | MAPT (0.51) | MAPTAAK1PAX8MAOB | |
| SCHEMBL12324089 | 0.71 | PAX8 (0.51) | MAPTPAX8MAOB | |
| SCHEMBL12323527 | 0.71 | MAPT (0.58) | MAPTPAX8MAOB | |
| SCHEMBL17432481 | 0.70 | MAPT (0.49) | MAPTAAK1PAX8MAOBSCN9A | |
| SCHEMBL17430158 | 0.70 | ESR2 (0.48) | MAPTAAK1PAX8MAOB | |
| SCHEMBL17430139 | 0.70 | PAX8 (0.49) | MAPTPAX8MAOB | |
| SCHEMBL18027579 | 0.69 | MAPT (0.60) | MAPTPAX8MAOBKAT8KAT6A | |
| SCHEMBL24150803 | 0.68 | MTNR1A (0.40) | HSD11B1HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049976-A1 | N-METHYL-4-(QUINOLIN-2-YL)PYRIDIN-2-AMINE COMPOUNDS | ABBVIE INC. (US) | 2024-03-07 | — | — | WO | disclosed |