Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 15/20 | 0.40 |
| ▸ | DAPK1 | P53355 | 3/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.39 |
| ▸ | BMP2K | Q9NSY1 | 3/20 | 0.39 |
| ▸ | GAK | O14976 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | DMPK | Q09013 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | MYLK2 | Q9H1R3 | 2/20 | 0.39 |
| ▸ | CIT | O14578 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.39 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.39 |
| ▸ | TLK1 | Q9UKI8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27364359 | 0.84 | MAPT (0.47) | AAK1MAPTBRAFCYP3A4 | |
| SCHEMBL27364556 | 0.82 | IRAK4 (0.47) | IRAK4AAK1DAPK1MKNK2BMP2K | |
| SCHEMBL27364477 | 0.81 | MAPT (0.37) | AAK1MAPT | |
| SCHEMBL14784481 | 0.74 | CNR2 (0.41) | — | |
| SCHEMBL17430152 | 0.74 | MAPT (0.49) | MAPTGSK3BDYRK1A | |
| SCHEMBL27364664 | 0.74 | IRAK4 (0.41) | IRAK4AAK1DAPK1MKNK2BMP2K | |
| SCHEMBL5958787 | 0.72 | MAPT (0.47) | MAPTGSK3BDYRK1A | |
| SCHEMBL21827970 | 0.71 | GSK3B (0.45) | GSK3BDYRK1A | |
| SCHEMBL10049511 | 0.71 | ESR2 (0.49) | MAPTGSK3BDYRK1A | |
| SCHEMBL27364273 | 0.71 | IRAK4 (0.43) | IRAK4AAK1DAPK1MKNK2BMP2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049976-A1 | N-METHYL-4-(QUINOLIN-2-YL)PYRIDIN-2-AMINE COMPOUNDS | ABBVIE INC. (US) | 2024-03-07 | — | — | WO | disclosed |