Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19379634 | 0.99 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BALDH1A1LMNA | |
| Bromide SCHEMBL8816763 | 0.93 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BALDH1A1LMNA | |
| SCHEMBL5888846 | 0.87 | — | — | |
| SCHEMBL6174357 | 0.86 | ALDH1A1 (0.51) | ADRA1DADRA1AADRA1BALDH1A1LMNA | |
| SCHEMBL16256927 | 0.85 | KCNH2 (0.49) | — | |
| SCHEMBL13316311 | 0.85 | ADRA1D (0.47) | ADRA1DADRA1AADRA1B | |
| SCHEMBL5888789 | 0.85 | SIGMAR1 (0.55) | ADRA1DADRA1AADRA1B | |
| SCHEMBL5888793 | 0.83 | OPRD1 (0.55) | — | |
| SCHEMBL28101802 | 0.83 | KCNH2 (0.57) | ADRA1DADRA1AADRA1B | |
| SCHEMBL11498959 | 0.83 | KCNH2 (0.53) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1061035-C | Phenylalkanolamine derivatives | HOFFMANN LA ROCHE (CH) | 2001-01-24 | — | — | CN | disclosed |