SCHEMBL27366044

SCHEMBL27366044

C=C(c1ccc(F)cc1)C(OC(=O)Nc1cc(Cl)cc(Cl)c1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.48
MEN1 O00255 6/20 0.48
MAOB P27338 1/20 0.43
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPT P10636 3/20 0.38
RAB9A P51151 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
LMNA P02545 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
GRM4 Q14833 1/20 0.38
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 2/20 0.38
HTR1E P28566 1/20 0.37
S1PR3 Q99500 1/20 0.37
KCNQ3 O43525 2/20 0.36
KCNQ2 O43526 2/20 0.36
KCNE1 P15382 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27368858 0.91 HPGD (0.42) KMT2AMEN1MAOBHPGDALOX15
SCHEMBL9835245 0.88 MEN1 (0.46) KMT2AMEN1MAOBHPGDALOX15
SCHEMBL27365358 0.79 CNR1 (0.43) KMT2AMEN1HPGDALOX15MAPT
SCHEMBL27368860 0.79 MEN1 (0.39) KMT2AMEN1MAOBHPGDALOX15
SCHEMBL27344658 0.74 SMN1; SMN2 (0.41) KMT2AMEN1HPGDMAPTRAB9A
SCHEMBL27309652 0.73 MEN1 (0.43) KMT2AMEN1HPGDMAPTRAB9A
SCHEMBL9837199 0.73 KLK7 (0.43) KMT2AMEN1MAOBHPGDALOX15
SCHEMBL27353072 0.70 FAAH (0.44) KMT2AMEN1MAPTLMNASENP7
SCHEMBL9835786 0.69 HPGD (0.43) KMT2AMEN1HPGDALOX15MAPT
SCHEMBL9835869 0.69 KMT2A (0.43) KMT2AMEN1MAOBHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed