Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27389832 | 0.89 | RXFP1 (0.42) | BRD4 | |
| SCHEMBL27370786 | 0.88 | TP53 (0.43) | ACAT1BRD4 | |
| SCHEMBL27451783 | 0.88 | ACAT1 (0.41) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL27393240 | 0.87 | JAK2 (0.40) | PDE4A | |
| SCHEMBL27368420 | 0.83 | KDM4E (0.39) | — | |
| SCHEMBL27391425 | 0.80 | TGFBR1 (0.41) | BRD4 | |
| SCHEMBL27480789 | 0.80 | ACAT1 (0.61) | ACAT1SOAT1PDE4A | |
| SCHEMBL27464490 | 0.80 | ACAT1 (0.54) | ACAT1SOAT1PDE4A | |
| SCHEMBL8597859 | 0.78 | FEN1 (0.37) | ACAT1SOAT1 | |
| SCHEMBL27483049 | 0.78 | ACAT1 (0.54) | ACAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1065243-C | Naphthyridine derivs. | SUMITOMO PHARMA (JP) | 2001-05-02 | — | — | CN | disclosed |
| CN-1191536-A | Naphthyridine derivs. | SUMITOMO PHARMA (JP) | 1998-08-26 | — | — | CN | disclosed |