Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PRKCB | P05771 | 4/20 | 0.37 |
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | MAP2 | P11137 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27534236 | 0.89 | POLB (0.41) | KDM4EPRKCBGSK3BPOLBNPC1 | |
| SCHEMBL27398847 | 0.88 | KDM4E (0.38) | KDM4EPRKCBGSK3BGAATACR1 | |
| SCHEMBL27392325 | 0.88 | TACR1 (0.40) | KDM4EPRKCBGSK3BPOLBALDH1A1 | |
| SCHEMBL27367479 | 0.87 | STK10 (0.41) | KDM4EPRKCBGSK3BPOLBRAB9A | |
| SCHEMBL27366469 | 0.83 | ACAT1 (0.42) | — | |
| SCHEMBL27392323 | 0.81 | MAP2 (0.40) | KDM4EPRKCBGSK3BPOLBNPC1 | |
| SCHEMBL6639070 | 0.78 | LPAR1 (0.53) | KDM4E | |
| SCHEMBL8597859 | 0.75 | FEN1 (0.37) | TACR1FEN1 | |
| SCHEMBL6634786 | 0.74 | PRKCB (0.44) | KDM4EPRKCBGSK3BPOLBNPC1 | |
| SCHEMBL27451783 | 0.72 | ACAT1 (0.41) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1065243-C | Naphthyridine derivs. | SUMITOMO PHARMA (JP) | 2001-05-02 | — | — | CN | disclosed |
| CN-1191536-A | Naphthyridine derivs. | SUMITOMO PHARMA (JP) | 1998-08-26 | — | — | CN | disclosed |