SCHEMBL27366601

SCHEMBL27366601

COc1cccc2cccc(CCN(C(C)C)C(C)C)c12

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.48
AOC3 Q16853 1/20 0.43
HTR6 P50406 3/20 0.43
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
RECQL P46063 1/20 0.39
BCHE P06276 1/20 0.37
CNR2 P34972 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27366100 0.87 HTR2A (0.65) HTR2AAOC3HTR6KDM4EGAA
SCHEMBL31332123 0.87 HTR2A (0.65) HTR2AAOC3HTR6KDM4EGAA
SCHEMBL27365914 0.83 HTR2A (0.61) HTR2AAOC3HTR6
SCHEMBL31331965 0.83 HTR2A (0.61) HTR2AAOC3HTR6
SCHEMBL27366009 0.80 BCHE (0.48) HTR2AAOC3HTR6BCHE
SCHEMBL27366012 0.80 BCHE (0.37) HTR2ABCHE
SCHEMBL31332092 0.79 BCHE (0.49) HTR2AAOC3BCHE
SCHEMBL27366592 0.79 BCHE (0.49) HTR2AAOC3BCHE
SCHEMBL27366013 0.79 HTR2A (0.64) HTR2AAOC3HTR6KDM4EGAA
SCHEMBL31332020 0.78 HTR2A (0.51) HTR2AAOC3HTR6BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 HTR2A 225/4885AOC3 703/4885HTR6 187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.