SCHEMBL31332020

SCHEMBL31332020

CCCN(C)CCc1cccc2cccc(OC)c12

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.51
HTR1D P28221 1/20 0.47
HTR1B P28222 1/20 0.47
SIGMAR1 Q99720 1/20 0.46
AOC3 Q16853 1/20 0.45
HTR6 P50406 2/20 0.45
CHRM2 P08172 1/20 0.43
BCHE P06276 2/20 0.42
ALOX5 P09917 1/20 0.40
PTGS2 P35354 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27366016 1.00 HTR2A (0.51) HTR2AHTR1DHTR1BSIGMAR1AOC3
SCHEMBL27366013 0.90 HTR2A (0.64) HTR2ASIGMAR1AOC3HTR6CHRM2
SCHEMBL27366592 0.87 BCHE (0.49) HTR2AHTR1DHTR1BAOC3BCHE
SCHEMBL31332092 0.87 BCHE (0.49) HTR2AHTR1DHTR1BAOC3BCHE
SCHEMBL31331965 0.84 HTR2A (0.61) HTR2AAOC3HTR6
SCHEMBL27365914 0.84 HTR2A (0.61) HTR2AAOC3HTR6
SCHEMBL8974349 0.82 ALOX5 (0.47) HTR2ASIGMAR1HTR6ALOX5PTGS2
SCHEMBL27366009 0.82 BCHE (0.48) HTR2AHTR1DHTR1BSIGMAR1AOC3
SCHEMBL31332123 0.79 HTR2A (0.65) HTR2ASIGMAR1AOC3HTR6CHRM2
SCHEMBL27366100 0.79 HTR2A (0.65) HTR2ASIGMAR1AOC3HTR6CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 HTR2A 225/4885HTR1D 522/4885HTR1B 161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.