Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27366654 | 0.86 | PDK1 (0.51) | PDK1KMT2AMAPTLIMK1MEN1 | |
| SCHEMBL1107076 | 0.81 | PDK1 (0.47) | PDK1KMT2AMAPTLIMK1MEN1 | |
| SCHEMBL537662 | 0.81 | PDK1 (0.47) | PDK1KMT2AMAPTLIMK1MEN1 | |
| SCHEMBL27366691 | 0.81 | PDK1 (0.46) | PDK1KMT2AMAPTLIMK1ALDH1A1 | |
| SCHEMBL27366718 | 0.79 | PDK1 (0.45) | PDK1KMT2AMAPTLIMK1MEN1 | |
| SCHEMBL1208500 | 0.79 | PDK1 (0.45) | PDK1KMT2AMAPTLIMK1MEN1 | |
| SCHEMBL2878655 | 0.78 | DRD2 (0.49) | PDK1KMT2AMAPTLIMK1CYP2C19 | |
| SCHEMBL2885395 | 0.77 | ALDH1A1 (0.49) | KMT2AMAPTMEN1CYP2C19ALDH1A1 | |
| SCHEMBL2884284 | 0.76 | KMT2A (0.41) | KMT2AMAPTMEN1CYP2C19ALDH1A1 | |
| SCHEMBL31188369 | 0.76 | DRD2 (0.49) | PDK1MAPTLIMK1CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |