Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LGMN | Q99538 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27366691 | 0.89 | PDK1 (0.46) | PDK1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL27366654 | 0.80 | PDK1 (0.51) | PDK1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL27366669 | 0.79 | PDK1 (0.50) | PDK1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL1107076 | 0.76 | PDK1 (0.47) | PDK1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL537662 | 0.76 | PDK1 (0.47) | PDK1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL1208500 | 0.73 | PDK1 (0.45) | PDK1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL2878655 | 0.72 | DRD2 (0.49) | PDK1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL27367050 | 0.70 | DRD2 (0.43) | PDK1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL408718 | 0.69 | PDK1 (0.47) | PDK1KDM4EALDH1A1KMT2ALIMK1 | |
| SCHEMBL30437453 | 0.69 | KDM4E (0.50) | PDK1KDM4EALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |