Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15946394 | 0.86 | DRD3 (0.51) | DRD2DRD3TSHRKDM4EALDH1A1 | |
| SCHEMBL27367039 | 0.86 | ALDH1A1 (0.45) | DRD2DRD3TSHRKDM4EALDH1A1 | |
| SCHEMBL20243993 | 0.81 | KDM4E (0.43) | DRD2DRD3TSHRKDM4EALDH1A1 | |
| SCHEMBL629772 | 0.81 | OPRK1 (0.48) | DRD2DRD3KDM4EALDH1A1KMT2A | |
| SCHEMBL10529754 | 0.80 | MAPK1 (0.46) | TSHRKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL21383104 | 0.80 | SHMT2 (0.46) | DRD2DRD3KDM4EALDH1A1KMT2A | |
| SCHEMBL30437653 | 0.80 | MAPK1 (0.46) | TSHRKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL10528687 | 0.79 | CYP4F2 (0.59) | DRD2DRD3KDM4EALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL10528366 | 0.79 | SHMT2 (0.45) | DRD2DRD3KDM4EALDH1A1KMT2A | |
| SCHEMBL630214 | 0.79 | DRD2 (0.51) | DRD2DRD3TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |