Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.59 |
| ▸ | MME | P08473 | 2/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736691 | 1.00 | ACE (0.59) | ACEMMEPGRADRA2AADRA2B | |
| SCHEMBL8821887 | 0.83 | PGR (0.50) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL10619759 | 0.78 | MMP2 (0.49) | ACEMMEPGRADRA2AADRA2B | |
| Bromobenzene SCHEMBL8220105 | 0.76 | ACE (0.56) | ACEMME | |
| SCHEMBL14665678 | 0.75 | PGR (0.53) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL2736655 | 0.75 | L3MBTL1 (0.54) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL337276 | 0.75 | L3MBTL1 (0.54) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL10489465 | 0.75 | PGR (0.58) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL2736656 | 0.75 | L3MBTL1 (0.54) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL2128162 | 0.75 | PGR (0.58) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088924-B2 | Pyridone derivatives having a binding activity to the cannabinoid type 2 receptor | SHIONOGI & CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20100081686-A1 | Pyridone derivatives having a binding activity to the cannabinoid type 2 recepter | TADA YUKIO | 2010-04-01 | — | — | US | disclosed |
| US-7652141-B2 | Immunosuppressants, analgesics, antiinflammatory agents | SHIONOGI & CO., LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20080312292-A1 | Antipruritics | YASUI KIYOSHI | 2008-12-18 | — | — | US | disclosed |
| US-20070027144-A1 | Novel use of cannabinoid receptor agonist | SHIONOGI & CO., LTD. (JP) | 2007-02-01 | — | — | US | disclosed |
| US-20070027144-A1 | Novel use of cannabinoid receptor agonist | SHIONOGI & CO., LTD. (JP) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027144-A1 | Novel use of cannabinoid receptor agonist | CNR2, CNR1, OPRM1 | ACE 3881/4885MME 3707/4885PGR 167/4885 |
| US-20100081686-A1 | Pyridone derivatives having a binding activity to the cannabinoid type 2 recepter | CNR2, CNR1, NPY2R | ACE 2761/4885MME 4296/4885PGR 38/4885 |
| US-20080312292-A1 | Antipruritics | CNR1, CNR2, OPRL1 | ACE 445/4885MME 149/4885PGR 646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.