Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27365346 | 0.82 | ALPL (0.44) | SIGMAR1DRD2ALDH1A1HPGDMAPT | |
| SCHEMBL19285630 | 0.77 | SIGMAR1 (0.42) | SIGMAR1DRD2ALDH1A1LMNAHPGD | |
| SCHEMBL6996637 | 0.73 | SIGMAR1 (0.46) | SIGMAR1DRD2ALDH1A1LMNAHPGD | |
| SCHEMBL27954125 | 0.68 | BACE1 (0.40) | SIGMAR1DRD2ALDH1A1LMNAHPGD | |
| SCHEMBL25835236 | 0.68 | SIGMAR1 (0.42) | SIGMAR1DRD2ALDH1A1LMNAHPGD | |
| SCHEMBL25237168 | 0.66 | CYP2D6 (0.39) | DRD2ALDH1A1HPGDRAB9ANPSR1 | |
| SCHEMBL25237587 | 0.65 | KMT2A (0.41) | DRD2ALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL6993020 | 0.62 | RARA (0.43) | SIGMAR1DRD2ALDH1A1LMNAHPGD | |
| SCHEMBL27333093 | 0.62 | ALDH1A1 (0.46) | SIGMAR1ALDH1A1LMNAHPGDBACE1 | |
| SCHEMBL22492411 | 0.60 | ALDH1A1 (0.51) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1055925-A | Pyridine derivate and preparation method thereof | ICI PLC (GB) | 1991-11-06 | — | — | CN | disclosed |