Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367125 | 0.79 | MCHR1 (0.39) | HTR2CCA1CA2ACHEMCHR1 | |
| SCHEMBL27367345 | 0.77 | PDK1 (0.38) | TSHRALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL27366767 | 0.68 | CNR2 (0.32) | — | |
| SCHEMBL27367322 | 0.65 | CCKBR (0.35) | NPC1RAB9AALDH1A1KDM4EMCHR1 | |
| SCHEMBL27367224 | 0.64 | AKR1C3 (0.45) | NPC1TSHRALDH1A1MEN1RECQL | |
| SCHEMBL27367305 | 0.64 | NPC1 (0.53) | NPC1RAB9AALDH1A1KMT2ALMNA | |
| SCHEMBL16715429 | 0.64 | HTR2C (0.55) | HTR2CHTR2BNPC1RAB9ATSHR | |
| SCHEMBL4773205 | 0.63 | HTR2C (1.00) | HTR2CHTR2B | |
| SCHEMBL11476520 | 0.63 | CA1 (0.53) | CA1CA2ACHE | |
| SCHEMBL20006885 | 0.62 | HTR1D (0.51) | HTR2CHTR2BNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |