Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367338 | 0.81 | ACHE (0.32) | GPR119 | |
| SCHEMBL27367313 | 0.76 | CCKBR (0.38) | CCKBRMCHR1NPC1RAB9ALMNA | |
| SCHEMBL13262741 | 0.70 | CA1 (0.48) | — | |
| SCHEMBL18430841 | 0.70 | ALDH1A1 (0.39) | MCHR1ALDH1A1CYP3A4 | |
| SCHEMBL13954518 | 0.69 | OPRK1 (0.36) | MCHR1ALDH1A1CYP3A4 | |
| SCHEMBL5991759 | 0.67 | OPRK1 (0.35) | MCHR1ALDH1A1CYP3A4 | |
| SCHEMBL12953718 | 0.67 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10ESR2 | |
| SCHEMBL27367125 | 0.67 | MCHR1 (0.39) | MCHR1 | |
| SCHEMBL6630069 | 0.67 | CYP2D6 (0.38) | HDAC8 | |
| SCHEMBL13957550 | 0.66 | CYP2D6 (0.35) | ALDH1A1KDM4EHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |