Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 7/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TAOK3 | Q9H2K8 | 3/20 | 0.37 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367100 | 0.80 | MCHR1 (0.38) | MCHR1DRD2ACHECA1CA2 | |
| SCHEMBL27367050 | 0.78 | DRD2 (0.43) | MCHR1DRD2ACHECA1CA2 | |
| SCHEMBL15866398 | 0.75 | ESR1 (0.47) | DRD2DRD3 | |
| SCHEMBL16171630 | 0.72 | CNR2 (0.43) | DRD2DRD3 | |
| SCHEMBL16171625 | 0.72 | CNR2 (0.43) | TAOK3 | |
| SCHEMBL15946396 | 0.71 | ESR1 (0.48) | — | |
| SCHEMBL15866397 | 0.71 | ESR1 (0.48) | — | |
| SCHEMBL13350380 | 0.70 | ESR1 (0.49) | DRD2DRD3 | |
| SCHEMBL6534296 | 0.69 | GHSR (0.49) | — | |
| SCHEMBL8178256 | 0.69 | NAAA (0.50) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |