Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 18/20 | 0.55 |
| ▸ | MERTK | Q12866 | 15/20 | 0.55 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367180 | 0.88 | AXL (0.57) | AXLMERTKTYRO3UBE2N | |
| SCHEMBL27365544 | 0.87 | MERTK (0.66) | AXLMERTKTYRO3MET | |
| SCHEMBL27366944 | 0.81 | MERTK (0.82) | AXLMERTKTYRO3 | |
| SCHEMBL27365489 | 0.81 | MET (0.58) | AXLMERTKTYRO3METFLT3 | |
| SCHEMBL27365768 | 0.81 | MERTK (0.65) | AXLMERTKTYRO3MET | |
| SCHEMBL27365552 | 0.78 | MERTK (0.65) | AXLMERTKTYRO3MET | |
| SCHEMBL31512159 | 0.78 | MERTK (0.77) | AXLMERTKTYRO3MET | |
| SCHEMBL27365492 | 0.78 | MERTK (0.77) | AXLMERTKTYRO3MET | |
| SCHEMBL27365767 | 0.77 | MERTK (0.66) | AXLMERTKTYRO3MET | |
| SCHEMBL32685072 | 0.75 | MERTK (0.67) | AXLMERTKTYRO3MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024039842-A2 | INHIBITORS OF TAM RECEPTORS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2024-02-22 | — | — | WO | disclosed |