Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.43 |
| ▸ | MMP13 | P45452 | 6/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367223 | 0.78 | AKR1C3 (0.39) | MMP2MMP13ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27367160 | 0.74 | CYP2C9 (0.52) | ALDH1A1SMN1; SMN2MAPTGAAMAPK1 | |
| SCHEMBL18770418 | 0.73 | L3MBTL1 (0.62) | ATMALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL3653336 | 0.72 | KMT2A (0.58) | ALDH1A1LMNAL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL17290764 | 0.71 | ALDH1A1 (0.50) | ATMALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL4977454 | 0.68 | KMT2A (0.53) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL20942845 | 0.68 | ADRB2 (0.57) | ALDH1A1MAPT | |
| SCHEMBL853199 | 0.65 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTGAAKMT2A | |
| SCHEMBL29362884 | 0.65 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTGAAKMT2A | |
| SCHEMBL29212110 | 0.64 | NPC1 (0.61) | ALDH1A1LMNAL3MBTL1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |