Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577961 | 0.81 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2GAACES2CES1 | |
| Hydrochloric Acid SCHEMBL5352593 | 0.79 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2GAACES2CES1 | |
| SCHEMBL1694938 | 0.77 | LMNA (0.41) | LMNASMN1; SMN2GAACES2CES1 | |
| SCHEMBL7505533 | 0.76 | LMNA (0.44) | LMNASMN1; SMN2GAACES2CES1 | |
| SCHEMBL9547589 | 0.73 | CES2 (0.44) | LMNASMN1; SMN2CES2CES1ALDH1A1 | |
| SCHEMBL7769262 | 0.72 | LMNA (0.55) | LMNASMN1; SMN2CES2CES1ALDH1A1 | |
| SCHEMBL11474378 | 0.71 | TSPO (0.53) | LMNASMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL11453187 | 0.71 | ELANE (0.45) | LMNASMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL3360546 | 0.71 | PTPN1 (0.43) | LMNASMN1; SMN2CES2CES1ALDH1A1 | |
| SCHEMBL9547540 | 0.71 | CES2 (0.39) | LMNASMN1; SMN2CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052854-A | The preparation method of 2-(2-furyl) thanomin | MONSANTO CO (US) | 1991-07-10 | — | — | CN | disclosed |