Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589614 | 0.81 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2KMT2APTPN1POLB | |
| SCHEMBL8589610 | 0.81 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2KMT2APTPN1POLB | |
| SCHEMBL4596550 | 0.79 | LMNA (0.40) | LMNASMN1; SMN2KMT2APTPN1POLB | |
| SCHEMBL6208282 | 0.73 | FOLH1 (0.50) | ALDH1A1MAPK1 | |
| SCHEMBL6208283 | 0.73 | FOLH1 (0.50) | ALDH1A1MAPK1 | |
| SCHEMBL11249889 | 0.73 | LMNA (0.49) | LMNASMN1; SMN2KMT2APKMALDH1A1 | |
| SCHEMBL1061794 | 0.73 | LMNA (0.49) | LMNASMN1; SMN2KMT2APKMALDH1A1 | |
| SCHEMBL2968427 | 0.73 | LMNA (0.49) | LMNASMN1; SMN2KMT2APKMALDH1A1 | |
| SCHEMBL27367529 | 0.72 | LMNA (0.45) | LMNASMN1; SMN2KMT2APTPN1POLB | |
| SCHEMBL27508739 | 0.72 | S1PR4 (0.42) | LMNASMN1; SMN2KMT2APTPN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121446-A1 | AMINOACYLASE AND ITS USE IN THE PRODUCTION OF D-AMINOACIDS | Chirotech Technology Limited (GB) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000023598-A1 | AMINOACYLASE AND ITS USE IN THE PRODUCTION OF D-AMINOACIDS | CHIROTECH TECHNOLOGY LIMITED (GB) | 2000-04-27 | — | — | WO | disclosed |