Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NEK2 | P51955 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10208272 | 0.91 | POLB (0.39) | POLBGAA | |
| SCHEMBL2736960 | 0.91 | GABRA1 (0.41) | POLBGAA | |
| SCHEMBL10207829 | 0.90 | ALDH1A1 (0.42) | POLBGAA | |
| SCHEMBL2736994 | 0.89 | POLB (0.38) | POLBGAA | |
| SCHEMBL2736633 | 0.88 | KDM4E (0.39) | HPGDMEN1KMT2A | |
| SCHEMBL10207266 | 0.88 | POLB (0.37) | POLBGAA | |
| SCHEMBL12309584 | 0.88 | — | — | |
| SCHEMBL10207673 | 0.85 | PSEN1 (0.38) | HPGDGAAMEN1KMT2A | |
| SCHEMBL2736652 | 0.85 | MAPT (0.37) | HPGDPOLBMEN1KMT2A | |
| SCHEMBL2737079 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402314-A1 | (Aza)indole derivative and use thereof for medical purposes | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |