Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10208272 | 0.95 | POLB (0.39) | POLBGAA | |
| SCHEMBL2736960 | 0.93 | GABRA1 (0.41) | POLBGAA | |
| SCHEMBL10207266 | 0.92 | POLB (0.37) | POLBGAA | |
| SCHEMBL2736633 | 0.92 | KDM4E (0.39) | — | |
| SCHEMBL10207829 | 0.92 | ALDH1A1 (0.42) | POLBGAA | |
| SCHEMBL2736782 | 0.89 | HPGD (0.42) | POLBGAA | |
| SCHEMBL10207673 | 0.88 | PSEN1 (0.38) | GAA | |
| SCHEMBL2736652 | 0.88 | MAPT (0.37) | POLB | |
| SCHEMBL12309561 | 0.87 | — | — | |
| SCHEMBL2736670 | 0.85 | MCHR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402314-A1 | (Aza)indole derivative and use thereof for medical purposes | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |