Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10208272 | 0.94 | POLB (0.39) | — | |
| SCHEMBL2736994 | 0.92 | POLB (0.38) | — | |
| SCHEMBL2736960 | 0.92 | GABRA1 (0.41) | — | |
| SCHEMBL10207266 | 0.91 | POLB (0.37) | — | |
| SCHEMBL10207829 | 0.91 | ALDH1A1 (0.42) | KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL2736782 | 0.88 | HPGD (0.42) | MEN1HPGDKMT2A | |
| SCHEMBL2737063 | 0.88 | PIM1 (0.47) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL12309565 | 0.87 | — | — | |
| SCHEMBL10207673 | 0.87 | PSEN1 (0.38) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL12336365 | 0.87 | L3MBTL1 (0.47) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402314-A1 | (Aza)indole derivative and use thereof for medical purposes | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |