SCHEMBL27367994

SCHEMBL27367994

CCCCC(=O)ONC(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
KMT2A Q03164 2/20 0.54
POLB P06746 2/20 0.54
MAPT P10636 1/20 0.54
CES2 O00748 3/20 0.51
CES1 P23141 3/20 0.51
NAAA Q02083 1/20 0.51
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
RECQL P46063 1/20 0.48
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
PRSS1 P07477 2/20 0.45
CTSG P08311 2/20 0.45
CTRB1 P17538 2/20 0.45
CMA1 P23946 2/20 0.45
PKM P14618 1/20 0.45
PTGS2 P35354 1/20 0.45
HDAC3 O15379 2/20 0.44
HDAC4 P56524 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11129975 0.95 NAAA (0.54) ALDH1A1KMT2APOLBMAPTCES2
SCHEMBL15993619 0.94 NAAA (0.56) ALDH1A1KMT2APOLBMAPTCES2
SCHEMBL26929523 0.92 NAAA (0.55) ALDH1A1KMT2APOLBMAPTCES2
SCHEMBL6886046 0.90 ALDH1A1 (0.58) ALDH1A1KMT2APOLBMAPTCES2
SCHEMBL8459980 0.87 ALDH1A1 (0.54) ALDH1A1KMT2APOLBMAPTKDM4E
SCHEMBL27556286 0.86 ALDH1A1 (0.66) ALDH1A1KMT2APOLBMAPTCES1
SCHEMBL28102734 0.86 LMNA (0.50) ALDH1A1KMT2APOLBMAPTKDM4E
SCHEMBL9574878 0.86 POLB (0.61) ALDH1A1POLBCES2CES1NAAA
SCHEMBL27540289 0.84 HDAC3 (0.54) ALDH1A1KMT2APOLBMAPTKDM4E
SCHEMBL27793167 0.84 SMN1; SMN2 (0.42) ALDH1A1KMT2APOLBMAPTCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117255626-A Amide compounds and their use as flavor modifiers 弗门尼舍公司 2023-12-19 CN disclosed
CN-105001098-A Method for preparing 3(R)/(S)-amidogen-1-butanol SHENGZHOU OIL CHEMICAL CO LTD 2015-10-28 CN disclosed
CN-104961640-A Preparation method of optically pure 3-amino-1-butanol SHENGZHOU GREASE AND CHEMICAL CO LTD 2015-10-07 CN disclosed
CN-100475786-C 4-hydroxypentanamide compound and preparation method and application thereof SHANGHAI INST MATERIA MEDICA (CN) 2009-04-08 CN disclosed
CN-1757635-A 4-hydroxypentanamide compound and preparation method and application thereof SHANGHAI PHARMACEUTICAL INST C (CN) 2006-04-12 CN disclosed
CN-1056141-C Piperazine derivatives MERCK PATENT GESELLSCHAFTR MIT (DE) 2000-09-06 CN disclosed
CN-1099759-A Piperazine derivatives MERCK PATENT GMBH (DE) 1995-03-08 CN disclosed