Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27540289 | 0.86 | HDAC3 (0.54) | LMNACYP1A2TSHRMAPTALDH1A1 | |
| SCHEMBL27367994 | 0.86 | ALDH1A1 (0.54) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL27277571 | 0.82 | SPHK1 (0.56) | MAPTALDH1A1MEN1KMT2APLK1 | |
| SCHEMBL11129975 | 0.81 | NAAA (0.54) | MAPTALDH1A1NPC1RAB9APOLB | |
| SCHEMBL15993619 | 0.80 | NAAA (0.56) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL28102743 | 0.79 | HTR4 (0.52) | CYP1A2TSHRPDE4DMAPTCYP2D6 | |
| SCHEMBL26929523 | 0.79 | NAAA (0.55) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9574878 | 0.79 | POLB (0.61) | LMNACYP1A2ALDH1A1NPC1RAB9A | |
| SCHEMBL28056642 | 0.79 | KDM4E (0.50) | TSHRALDH1A1SMN1; SMN2KDM4EHDAC3 | |
| SCHEMBL10652248 | 0.78 | LMNA (0.61) | LMNACYP1A2CYP3A4TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102844327-B | Template-fixed peptidomimetics with CXCR7 modulatory activity | 波利弗尔股份公司 | 2016-10-26 | — | — | CN | disclosed |