SCHEMBL27368069

SCHEMBL27368069

CC=C(C)C(OC(=O)Nc1cc(C(C)(C)C)c(Cl)cc1F)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.33
PTGS1 P23219 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
DHODH Q02127 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9837437 0.76 LMNA (0.33) POLBAPEX1DHODH
SCHEMBL27676769 0.74 KMT2A (0.49)
SCHEMBL9836020 0.74 ALDH1A1 (0.49)
SCHEMBL8998088 0.72 LMNA (0.34) POLBDHODH
SCHEMBL8998090 0.72 LMNA (0.34) POLBDHODH
SCHEMBL9836339 0.72 DHODH (0.40) POLBDHODH
SCHEMBL10560773 0.71 TDP1 (0.46)
SCHEMBL9836639 0.71 DHODH (0.39) POLBDHODH
SCHEMBL8998049 0.70 ALDH1A1 (0.34) DHODH
SCHEMBL8998044 0.70 ALDH1A1 (0.34) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed