Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 6/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998049 | 1.00 | ALDH1A1 (0.34) | ALDH1A1LMNATSHRNPSR1L3MBTL1 | |
| SCHEMBL8998088 | 0.91 | LMNA (0.34) | ALDH1A1LMNATSHRNPSR1L3MBTL1 | |
| SCHEMBL8998090 | 0.91 | LMNA (0.34) | ALDH1A1LMNATSHRNPSR1L3MBTL1 | |
| SCHEMBL8998061 | 0.89 | ALDH1A1 (0.35) | ALDH1A1LMNATSHRNPSR1L3MBTL1 | |
| SCHEMBL9836639 | 0.84 | DHODH (0.39) | ALDH1A1LMNATSHRNPSR1L3MBTL1 | |
| SCHEMBL9407131 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNATSHRNPSR1L3MBTL1 | |
| SCHEMBL9868327 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRNPSR1L3MBTL1 | |
| SCHEMBL8083816 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRNPSR1L3MBTL1 | |
| SCHEMBL9835551 | 0.80 | DHODH (0.38) | LMNATSHRNPSR1L3MBTL1DHODH | |
| SCHEMBL8998070 | 0.79 | L3MBTL1 (0.46) | ALDH1A1LMNATSHRNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496347-B1 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEM RES (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5391807-A | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0496347-A2 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |