SCHEMBL27368260

SCHEMBL27368260

C=CC(=O)Oc1ccccc1C(=O)OC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.45
HSD17B10 Q99714 5/20 0.45
HPGD P15428 4/20 0.45
MAPT P10636 3/20 0.45
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
ELANE P08246 2/20 0.44
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
SLC6A3 Q01959 1/20 0.42
NPSR1 Q6W5P4 1/20 0.40
ALDH1A1 P00352 2/20 0.39
ESR1 P03372 1/20 0.39
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39
HMGB1 P09429 1/20 0.39
TSHR P16473 1/20 0.39
GGT1 P19440 1/20 0.39
PTGS1 P23219 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16681024 0.87 THRB (0.39) KDM4EHSD17B10HPGDMAPTTHRA
Methyl Salicylate Acrylic Ester SCHEMBL1054590 0.83 SLC6A3 (0.61) KDM4EHSD17B10HPGDMAPTTHRA
SCHEMBL21710499 0.82 MAPT (0.54) KDM4EHSD17B10HPGDMAPTELANE
SCHEMBL1282947 0.82 HSD17B10 (0.50) KDM4EHSD17B10HPGDMAPTELANE
SCHEMBL9707104 0.81 THRB (0.47) KDM4EHSD17B10HPGDMAPTTHRA
SCHEMBL4597023 0.81 HSD17B10 (0.50) KDM4EHSD17B10HPGDMAPTELANE
SCHEMBL29574954 0.81 KDM4E (0.49) KDM4EHSD17B10HPGDMAPTELANE
SCHEMBL4731573 0.81 HSD17B10 (0.63) KDM4EHSD17B10HPGDMAPTELANE
SCHEMBL5834545 0.81 KDM4E (0.50) KDM4EHSD17B10HPGDMAPTTHRA
SCHEMBL16680530 0.80 NR1H2 (0.34) KDM4EHSD17B10HPGDMAPTTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024092041-A1 CURABLE COMPOSITIONS COMPRISING A POLYMERIZABLE REACTIVE DILUENT FOR FABRICATION OF ORTHODONTIC APPLIANCES ALIGN TECHNOLOGY, INC. (US) 2024-05-02 WO disclosed