SCHEMBL16680530

SCHEMBL16680530

C=CC(=O)Oc1ccc(N)cc1C(=O)OC(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.34
ALDH1A1 P00352 3/20 0.34
GAA P10253 2/20 0.34
KRAS P01116 1/20 0.34
THRB P10828 5/20 0.33
KDM4E B2RXH2 3/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 2/20 0.33
HIF1A Q16665 2/20 0.33
THRA P10827 1/20 0.33
GLA P06280 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
TYMS P04818 1/20 0.32
ALOX5 P09917 1/20 0.32
HTR2A P28223 1/20 0.32
CYP3A4 P08684 2/20 0.31
KDR P35968 2/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
ADORA3 P0DMS8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16681357 0.82 NR1H2 (0.35) NR1H2ALDH1A1GAATHRBKDM4E
SCHEMBL27368260 0.80 KDM4E (0.45) ALDH1A1THRBKDM4EMAPTHPGD
SCHEMBL596796 0.80 ALDH1A1 (0.39) NR1H2ALDH1A1GAATHRBKDM4E
SCHEMBL5267229 0.80 KDM4E (0.47) ALDH1A1GAATHRBKDM4EMAPT
SCHEMBL29716033 0.80 KDM4E (0.47) ALDH1A1GAATHRBKDM4EMAPT
SCHEMBL16681024 0.80 THRB (0.39) ALDH1A1GAATHRBKDM4EMAPT
SCHEMBL596941 0.77 LMNA (0.41) ALDH1A1GAAMAPTTYMSCYP3A4
SCHEMBL7263006 0.77 PTGDR2 (0.39) NR1H2ALDH1A1GAAKDM4EMAPT
SCHEMBL31656226 0.77 MAPT (0.40) NR1H2ALDH1A1GAAKDM4EMAPT
Methacrylic Acid SCHEMBL30185393 0.76 ALDH1A1 (0.43) ALDH1A1GAATHRBKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9128378-B2 Forming conductive metal patterns with reactive polymers EASTMAN KODAK COMPANY (US) 2015-09-08 US disclosed
US-20150125667-A1 FORMING CONDUCTIVE METAL PATTERNS WITH REACTIVE POLYMERS BANK OF AMERICA, N.A., AS AGENT 2015-05-07 US disclosed