SCHEMBL16681024

SCHEMBL16681024

C=CC(=O)Oc1cccc(C(=O)OC(C)(C)C)c1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.39
THRA P10827 1/20 0.39
KDM4E B2RXH2 3/20 0.36
MAPT P10636 3/20 0.36
HPGD P15428 2/20 0.36
ALDH1A1 P00352 2/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 2/20 0.36
TYMS P04818 1/20 0.35
ELANE P08246 2/20 0.35
GRM6 O15303 1/20 0.33
SLC7A5 Q01650 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 1/20 0.33
KDM1A O60341 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32
CA12 O43570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27368260 0.87 KDM4E (0.45) THRBTHRAKDM4EMAPTHPGD
SCHEMBL16680460 0.82 THRB (0.40) THRBTHRAKDM4EMAPTHPGD
SCHEMBL16681319 0.82 ELANE (0.36) THRBKDM4EMAPTHPGDALDH1A1
SCHEMBL16680530 0.80 NR1H2 (0.34) THRBTHRAKDM4EMAPTHPGD
SCHEMBL5614479 0.78 ALDH1A1 (0.38) THRBKDM4EMAPTHPGDALDH1A1
SCHEMBL6131099 0.76 MAPK3 (0.40) THRBKDM4EMAPTHPGDALDH1A1
SCHEMBL6542697 0.76 ALDH1A1 (0.46) KDM4EMAPTHPGDALDH1A1GLA
SCHEMBL9707104 0.75 THRB (0.47) THRBTHRAKDM4EMAPTHPGD
SCHEMBL2940954 0.74 G6PD (0.55) KDM4EMAPTHPGDALDH1A1HIF1A
SCHEMBL222447 0.74 G6PD (0.50) KDM4EHPGDALDH1A1HSD17B10GRM6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9128378-B2 Forming conductive metal patterns with reactive polymers EASTMAN KODAK COMPANY (US) 2015-09-08 US disclosed
US-20150125667-A1 FORMING CONDUCTIVE METAL PATTERNS WITH REACTIVE POLYMERS BANK OF AMERICA, N.A., AS AGENT 2015-05-07 US disclosed