Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689363 | 1.00 | CYP19A1 (0.53) | CYP19A1KIF11CYP3A4CYP3A5TLR8 | |
| SCHEMBL24400587 | 0.83 | PDE4B (0.43) | KIF11CYP3A4CYP3A5CYP11B1CYP11B2 | |
| SCHEMBL458229 | 0.80 | KIF11 (0.68) | CYP19A1KIF11CYP3A4CYP3A5KDM4E | |
| SCHEMBL15832079 | 0.80 | RAB9A (0.49) | TLR8CYP11B1CYP11B2KDM4EMEN1 | |
| SCHEMBL27368527 | 0.80 | CYP19A1 (0.57) | CYP19A1CYP3A4SCN9ACYP11B1CYP11B2 | |
| SCHEMBL30689372 | 0.80 | CYP19A1 (0.57) | CYP19A1CYP3A4SCN9ACYP11B1CYP11B2 | |
| SCHEMBL21186223 | 0.80 | ALDH1A1 (0.47) | KIF11CYP3A4TLR8SCN9AMEN1 | |
| SCHEMBL30689378 | 0.76 | CYP19A1 (0.57) | CYP19A1CYP3A4SCN9AKDM4ELMNA | |
| SCHEMBL27368501 | 0.76 | CYP19A1 (0.57) | CYP19A1CYP3A4SCN9AKDM4ELMNA | |
| SCHEMBL15814057 | 0.76 | ALDH1A1 (0.49) | TLR8SCN9AKDM4ELMNAPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |