Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5052222 | 0.86 | CES2 (0.35) | CES2CES1CA12CA1CA9 | |
| SCHEMBL67496 | 0.82 | ALDH1A1 (0.42) | CES2CES1CA12CA1CA9 | |
| SCHEMBL851628 | 0.82 | CES2 (0.46) | CES2CES1CA12CA1CA9 | |
| SCHEMBL28280990 | 0.80 | PTGES2 (0.35) | CES2CES1CA12CA1CA9 | |
| SCHEMBL28166420 | 0.79 | CA1 (0.43) | CES2CES1CA12CA1CA9 | |
| SCHEMBL1603078 | 0.79 | CA1 (0.46) | CES2CES1CA1CA9SOS1 | |
| SCHEMBL28282385 | 0.78 | KDM1A (0.34) | CES2CES1CA12CA1CA9 | |
| SCHEMBL3848319 | 0.78 | CES2 (0.33) | CES2CES1CA12CA1CA9 | |
| SCHEMBL9394710 | 0.76 | IDO1 (0.38) | CES2CES1CA12CA1CA9 | |
| SCHEMBL449836 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104045645-B | The synthetic method of harringtonine C ring intermediates | 河北科技大学 | 2018-10-19 | — | — | CN | claimed |
| CN-103265436-B | Method for synthesising 1,5,9-trinitro-2,3,6,7,10,11-hexa-alkoxy triphenylene | UNIV SHAANXI NORMAL | 2015-03-18 | — | — | CN | claimed |
| CN-110325531-A | Benzsulfamide and its purposes as therapeutic agent | 泽农医药公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-109526219-A | Benzsulfamide and its purposes as therapeutic agent | 泽农医药公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-108698982-A | FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF | 日产化学工业株式会社 | 2018-10-23 | — | — | CN | disclosed |
| CN-104045645-B | The synthetic method of harringtonine C ring intermediates | 河北科技大学 | 2018-10-19 | — | — | CN | disclosed |
| CN-105073114-B | Medicine for respiratory disorder | 第三共株式会社 | 2017-07-28 | — | — | CN | disclosed |
| CN-103265436-B | Method for synthesising 1,5,9-trinitro-2,3,6,7,10,11-hexa-alkoxy triphenylene | UNIV SHAANXI NORMAL | 2015-03-18 | — | — | CN | disclosed |
| CN-104045646-A | Synthetic method of harringtonine intermediate with D-ring | UNIV HEBEI SCIENCE & TECH | 2014-09-17 | — | — | CN | disclosed |
| CN-103265436-A | Method for synthesising 1,5,9-trinitro-2,3,6,7,10,11-hexa-alkoxy triphenylene | UNIV SHAANXI NORMAL | 2013-08-28 | — | — | CN | disclosed |
| CN-101628888-B | Inhibitors of cytosolic phospholipase a2 | WYETH CORP | 2012-05-23 | — | — | CN | disclosed |
| CN-101628888-A | Inhibitors of cytosolic phospholipase A2 | WYETH CORP | 2010-01-20 | — | — | CN | disclosed |
| CN-100503566-C | Cytosolic phospholipase A2 inhibitors | WYETH CORP (US) | 2009-06-24 | — | — | CN | disclosed |
| CN-1249039-C | Inhibitors of 11 beta-hydroxysteroid dehydrogenase type I | BIOVITRUM AB (SE) | 2006-04-05 | — | — | CN | disclosed |
| CN-1617855-A | Cytosolic phospholipase A2Inhibitors | WYETH CORP (US) | 2005-05-18 | — | — | CN | disclosed |
| CN-1438997-A | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type I | BIOVITRUM AB (SE) | 2003-08-27 | — | — | CN | disclosed |
| CN-1165144-A | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-11-19 | — | — | CN | disclosed |
| CN-1165143-A | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-11-19 | — | — | CN | disclosed |
| CN-1066266-A | PHOSPHOSULFONATE HERBICIDES | ROHM & HAAS (US) | 1992-11-18 | — | — | CN | disclosed |