Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27963700 | 0.90 | ACHE (0.48) | CES2CES1ACHENFE2L2PARP1 | |
| SCHEMBL5014205 | 0.90 | CES2 (0.48) | CES2CES1ACHENFE2L2PARP1 | |
| SCHEMBL27487823 | 0.87 | TAAR1 (0.54) | PTPN1CYP3A4PTGS1PTGS2 | |
| SCHEMBL27703350 | 0.86 | CES2 (0.48) | CES2CES1ACHENFE2L2PARP1 | |
| SCHEMBL1170349 | 0.85 | MEN1 (0.50) | CES2CES1ACHENFE2L2PTPN1 | |
| SCHEMBL287677 | 0.84 | MAOB (0.43) | CES2CES1ACHENFE2L2PARP1 | |
| SCHEMBL4618588 | 0.84 | ACHE (0.74) | CES2CES1ACHENFE2L2RAB9A | |
| SCHEMBL27369528 | 0.82 | CES2 (0.43) | CES2CES1CA12CA1CA2 | |
| SCHEMBL13329 | 0.82 | — | — | |
| SCHEMBL67448 | 0.80 | ALDH1A1 (0.52) | NFE2L2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11911372-B2 | Compounds | CTXT PTY LTD (AU) | 2024-02-27 | — | — | US | disclosed |
| US-20210213004-A1 | Compounds | CTXT PTY LTD (AU) | 2021-07-15 | — | — | US | disclosed |
| US-20200138827-A1 | SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LIMITED (GB) | 2020-05-07 | — | — | US | disclosed |
| EP-3642184-A1 | SMALL MOLECULE MODULATORS OF HUMAN STING | Curadev Pharma Limited (GB) | 2020-04-29 | — | — | EP | disclosed |
| WO-2018234805-A1 | SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LIMITED (GB) | 2018-12-27 | — | — | WO | disclosed |
| CN-106478843-B | A kind of double oxime ester lightlike initiating agents containing thiphene ring and its preparation method and application | 同济大学 | 2017-12-26 | — | — | CN | disclosed |
| CN-106749317-A | A kind of azepine penthienate [2,3 d] pyrimidone benzsulfamide analog derivative and purposes | 中国科学院新疆理化技术研究所 | 2017-05-31 | — | — | CN | disclosed |
| CN-106220618-A | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | 阿勒根公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-103380115-B | Sulfur derivatives as chemokine receptor modulators | 阿勒根公司 | 2016-08-24 | — | — | CN | disclosed |
| US-9115086-B2 | Therapeutic compositions and related methods of use | AGIOS PHARMACEUTICALS, INC. (US) | 2015-08-25 | — | — | US | disclosed |
| WO-2008054288-A1 | 8-SULFONYL-L, 3, 4, 8-TETRAHYDR0-2H- [1, 4] OXAZEPINO [6, 7-E] INDOLE DERIVATIVES AND THEIR USE AS 5-HT6 RECEPTOR LIGANDS | BIOVITRUM AB (PUBL) (SE) | 2008-05-08 | — | — | WO | disclosed |
| US-20070249050-A1 | Substituted aromatic compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP. (US) | 2007-10-25 | — | — | US | disclosed |
| WO-2007087441-A2 | SUBSTITUTED AROMATIC COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | disclosed |
| US-6818772-B2 | DIETETICS, SLEEP DISORDERS, EATING DISORDERS, SEXUAL DISORDERS, CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | ABBOTT LABORATORIES | 2004-11-16 | — | — | US | disclosed |
| US-20030229119-A1 | Antagonists of melanin concentrating hormone effects on the melanin concetrating hormone receptor | ABBVIE INC. | 2003-12-11 | — | — | US | disclosed |
| WO-2003070244-A1 | ANTAGONIST OF MELANIN CONCENTRATING HORMONE AND THEIR USES | ABBOTT LABORATORIES (US) | 2003-08-28 | — | — | WO | disclosed |
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |
| EP-0686873-B1 | Color photographic element containing new epoxy scavengers for residual magenta coupler | EASTMAN KODAK CO (US) | 2000-04-19 | — | — | EP | disclosed |
| US-5543276-A | DISCOLORATION INHIBITION | EASTMAN KODAK COMPANY (US) | 1996-08-06 | — | — | US | disclosed |
| EP-0686873-A1 | Color photographic element containing new epoxy scavengers for residual magenta coupler | EASTMAN KODAK COMPANY (US) | 1995-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249050-A1 | Substituted aromatic compounds for inflammation and immune-related uses | CCR1, NLRP1, NLRP3 | CES2 2356/4885CES1 391/4885ACHE 3532/4885 |
| US-20030229119-A1 | Antagonists of melanin concentrating hormone effects on the melanin concetrating hormone receptor | MCHR1, MCHR2, MC1R | CES2 2237/4885CES1 3505/4885ACHE 1932/4885 |
| US-20200138827-A1 | SMALL MOLECULE MODULATORS OF HUMAN STING | STING1, IRF3, CGAS | CES2 4763/4885CES1 4122/4885ACHE 4849/4885 |
| US-20210213004-A1 | Compounds | SLC10A1, ABCB11, REN | CES2 662/4885CES1 921/4885ACHE 1366/4885 |
| US-11911372-B2 | Compounds | SLC10A1, ABCB11, REN | CES2 662/4885CES1 921/4885ACHE 1366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.