SCHEMBL27369736

SCHEMBL27369736

CC(C)(C)OC(=O)N1CCC(n2ccc(O)cc2=O)CC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 7/20 0.49
KDM4E B2RXH2 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
HCAR1 Q9BXC0 1/20 0.47
ESR2 Q92731 1/20 0.46
PTPN2 P17706 1/20 0.45
PTPN1 P18031 1/20 0.45
PTPN6 P29350 1/20 0.45
TP53 P04637 1/20 0.45
KMT2A Q03164 1/20 0.45
PRKCG P05129 1/20 0.45
PRKCB P05771 1/20 0.45
PRKCA P17252 1/20 0.45
PRKCH P24723 1/20 0.45
PRKCE Q02156 1/20 0.45
PRKCD Q05655 1/20 0.45
ALDH1A1 P00352 1/20 0.44
CTSD P07339 1/20 0.43
CTSE P14091 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16670233 0.86 FPR2 (0.48) GPR119KDM4EMAPTTHRBHCAR1
SCHEMBL21245743 0.86 GPR119 (0.48) GPR119KDM4EMAPTTHRBHCAR1
SCHEMBL30859596 0.85 GPR119 (0.50) GPR119KDM4EMAPTTHRBHCAR1
SCHEMBL27370026 0.85 GPR119 (0.47) GPR119KDM4EMAPTTHRBHCAR1
SCHEMBL25213516 0.84 GPR119 (0.46) GPR119KDM4EMAPTTHRBHCAR1
SCHEMBL16669749 0.83 ALDH1A1 (0.46) GPR119KDM4EMAPTTHRBHCAR1
SCHEMBL14334645 0.83 GPR119 (0.59) GPR119KDM4EMAPTTHRBHCAR1
SCHEMBL31701701 0.82 GPR119 (0.50) GPR119KDM4EMAPTTHRBHCAR1
SCHEMBL14824043 0.81 GPR119 (0.51) GPR119KDM4EMAPTTHRBTP53
SCHEMBL16670428 0.81 YAP1 (0.53) GPR119KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024073475-A9 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS (US) 2025-04-24 WO disclosed
WO-2024073475-A1 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed
WO-2024073475-A1 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed