SCHEMBL30859604

SCHEMBL30859604

Cc1cn(C2CCN(C(=O)OC(C)(C)C)CC2)c(=O)c(C=O)c1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 5/20 0.41
HCAR1 Q9BXC0 1/20 0.41
TP53 P04637 1/20 0.40
PRKCG P05129 1/20 0.40
PRKCB P05771 1/20 0.40
PRKCA P17252 1/20 0.40
PRKCH P24723 1/20 0.40
PRKCE Q02156 1/20 0.40
PRKCD Q05655 1/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
KMT2A Q03164 1/20 0.40
EPHX2 P34913 2/20 0.38
STS P08842 1/20 0.38
PTPN2 P17706 1/20 0.38
PTPN1 P18031 1/20 0.38
PTPN6 P29350 1/20 0.38
PKM P14618 1/20 0.38
CTSD P07339 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30859550 0.85 KRAS (0.36) GPR119
SCHEMBL30859584 0.83 TP53 (0.42) GPR119HCAR1TP53PRKCGPRKCB
SCHEMBL27369897 0.80 GPR119 (0.44) GPR119HCAR1TP53PRKCGPRKCB
SCHEMBL30859558 0.72 PRKCG (0.42) GPR119HCAR1TP53PRKCGPRKCB
SCHEMBL25150709 0.72 FPR2 (0.46) GPR119HCAR1TP53PRKCGPRKCB
SCHEMBL30398757 0.72 FPR2 (0.46) GPR119HCAR1TP53PRKCGPRKCB
SCHEMBL30859564 0.71 GPR119 (0.44) GPR119HCAR1PRKCGPRKCBPRKCA
SCHEMBL3248282 0.71 HCAR1 (0.49) GPR119HCAR1TP53PRKCGPRKCB
SCHEMBL28746214 0.70 HCAR1 (0.46) GPR119HCAR1TP53PRKCGPRKCB
SCHEMBL30910260 0.70 GPR119 (0.45) GPR119HCAR1TP53PRKCGPRKCB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024073475-A9 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS (US) 2025-04-24 WO disclosed
WO-2024073475-A1 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed