Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28104238 | 0.74 | GPR35 (0.55) | PLA2G4AMEN1ALDH1A1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL4105337 | 0.74 | TDP1 (0.39) | MEN1ALDH1A1MAPTKMT2AGPR35 | |
| SCHEMBL27682582 | 0.73 | ALDH1A1 (0.50) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL30950689 | 0.71 | PLA2G2A (0.42) | CA2PLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL29188283 | 0.71 | PLA2G2A (0.42) | CA2PLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL28234678 | 0.69 | PLA2G2A (0.47) | CA2PLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL2470505 | 0.69 | DAO (0.39) | ALDH1A1MAPTHTTKMT2AGPR35 | |
| SCHEMBL20303097 | 0.67 | ALDH1A1 (0.42) | MEN1ALDH1A1MAPTKMT2AATM | |
| SCHEMBL21543944 | 0.67 | GRM6 (0.43) | CA2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9430732 | 0.66 | GPR35 (0.44) | MEN1ALDH1A1KMT2AGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1066448-C | Amide derivatives | OTSUKA PHARMA CO LTD (JP) | 2001-05-30 | — | — | CN | disclosed |
| CN-1221419-A | Amide derivatives | OTSUKA PHARMA CO LTD (JP) | 1999-06-30 | — | — | CN | disclosed |