Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019128 | 0.81 | HRH3 (0.42) | KMT2AMEN1HRH3SLC6A3HTT | |
| SCHEMBL27460790 | 0.80 | P2RX4 (0.35) | POLBKMT2ASMN1; SMN2HRH3HTT | |
| SCHEMBL28638180 | 0.72 | TAAR1 (0.42) | POLBTAAR1KMT2ACYP2C19MEN1 | |
| SCHEMBL13374859 | 0.72 | KCNH2 (0.44) | TAAR1KMT2ACYP2C19MEN1CYP2D6 | |
| SCHEMBL3852893 | 0.72 | KCNH2 (0.44) | TAAR1KMT2ACYP2C19MEN1CYP2D6 | |
| SCHEMBL8866412 | 0.68 | SIGMAR1 (0.42) | POLB | |
| SCHEMBL23878272 | 0.68 | TAAR1 (0.47) | POLBTAAR1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL27757638 | 0.67 | KCNH2 (0.48) | KMT2ACYP2C19MEN1CYP2D6CYP1A2 | |
| SCHEMBL25241870 | 0.67 | LMNA (0.43) | POLBKMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL11836556 | 0.66 | SLC6A3 (0.49) | HRH3SLC6A3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1083453-C | Fused imidazole derivatives as multidrug resistance modulators | JANSSEN PHARMACEUTICA NV (BE) | 2002-04-24 | — | — | CN | disclosed |
| CN-1211985-A | Fused imidazole derivatives as multidrug resistance modulators | JANSSEN PHARMACEUTICA NV (BE) | 1999-03-24 | — | — | CN | disclosed |