Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27757638 | 0.85 | KCNH2 (0.48) | TNK2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL27371963 | 0.81 | POLB (0.40) | HRH3HTTMEN1KMT2ASLC6A3 | |
| SCHEMBL9762432 | 0.76 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL9761690 | 0.76 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL9761330 | 0.76 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL9762424 | 0.74 | AVPR1A (0.47) | ALDH1A1KCNH2 | |
| SCHEMBL11836556 | 0.72 | SLC6A3 (0.49) | HRH3HTTDRD2SLC6A3SIGMAR1 | |
| SCHEMBL27460790 | 0.72 | P2RX4 (0.35) | HRH3HTTALDH1A1LMNAKMT2A | |
| SCHEMBL8543898 | 0.71 | TLR8 (0.50) | HTTALDH1A1LMNAKMT2ARAB9A | |
| SCHEMBL10400588 | 0.71 | HTT (0.47) | HTTALDH1A1LMNAKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101410114-B | A3 adenosine receptor allosteric modulators | US GOV HEALTH & HUMAN SERV (US) | 2012-07-04 | — | — | CN | claimed |
| CN-101410114-A | A3 adenosine receptor allosteric modulators | US GOV HEALTH & HUMAN SERV (US) | 2009-04-15 | — | — | CN | claimed |
| CN-104619323-A | A3 adenosine receptor ligands for use in treatment of a sexual dysfunction | CAN FITE BIOPHARMA LTD | 2015-05-13 | — | — | CN | disclosed |
| CN-101410114-B | A3 adenosine receptor allosteric modulators | US GOV HEALTH & HUMAN SERV (US) | 2012-07-04 | — | — | CN | disclosed |
| CN-101410114-A | A3 adenosine receptor allosteric modulators | US GOV HEALTH & HUMAN SERV (US) | 2009-04-15 | — | — | CN | disclosed |