Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15465903 | 0.84 | MAOB (0.46) | MEN1KMT2AAKR1C3MAPTMMP2 | |
| SCHEMBL5726036 | 0.84 | MAPT (0.56) | MEN1KMT2AMAPTNPSR1NPC1 | |
| SCHEMBL26281033 | 0.83 | DRD2 (0.46) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL27740593 | 0.83 | MAPT (0.43) | MEN1KMT2AADRB1AKR1C3MAPT | |
| SCHEMBL28699851 | 0.81 | ALDH1A1 (0.62) | MEN1KMT2AMAPTHTT | |
| SCHEMBL21761955 | 0.81 | ADRB1 (0.49) | MEN1KMT2AADRB1MAPTCTSG | |
| SCHEMBL29310078 | 0.81 | KMT2A (0.46) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL1811119 | 0.80 | CTSC (0.36) | — | |
| SCHEMBL28719456 | 0.80 | CTSC (0.41) | KMT2AMAPT | |
| SCHEMBL28967198 | 0.80 | CTSC (0.36) | KMT2AMAPTNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105363-A1 | PYRIDONE AND PYRIMIDINONE INHIBITORS OF HEMATOPOIETIC PROGENITOR KINASE 1 | CURADEV PHARMA LTD (GB) | 2024-05-23 | — | — | WO | disclosed |