Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27350198 | 0.80 | AOC3 (0.50) | L3MBTL1SIGMAR1HDAC3HDAC1HDAC2 | |
| SCHEMBL22327659 | 0.80 | L3MBTL1 (0.43) | L3MBTL1SIGMAR1 | |
| SCHEMBL10285568 | 0.78 | CTSK (0.43) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL1926702 | 0.78 | L3MBTL1 (0.41) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL26995518 | 0.77 | L3MBTL1 (0.48) | L3MBTL1SIGMAR1HDAC3HDAC1HDAC2 | |
| SCHEMBL12514549 | 0.77 | L3MBTL1 (0.41) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL3640549 | 0.76 | AOC3 (0.47) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL12514163 | 0.76 | ADRB2 (0.39) | L3MBTL1SIGMAR1HDAC3HDAC1HDAC2 | |
| SCHEMBL8583347 | 0.76 | MAOA (0.47) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL5442678 | 0.76 | FFAR1 (0.49) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1310905-C | Antivirally active heterocyclic azahexane derivatives | NOVARTIS AG (CH) | 2007-04-18 | — | — | CN | disclosed |
| CN-1616453-A | Antivirally active heterocyclic azahexane derivatives | NOVARTIS AG (CH) | 2005-05-18 | — | — | CN | disclosed |
| CN-1193010-C | Heterocyclic azahexane derivatives with antiviral activity | NOVARTIS AG (CH) | 2005-03-16 | — | — | CN | disclosed |
| CN-1082508-C | Heterocyclic azahexane derivatives with antiviral activity | NOVARTIS AG (CH) | 2002-04-10 | — | — | CN | disclosed |
| CN-1319587-A | Heterocyclic azahexane derivatives with antiviral activity | NOVARTIS AG (CH) | 2001-10-31 | — | — | CN | disclosed |
| CN-1216539-A | Heterocyclic azahexane derivatives with antiviral activity | NOVARTIS AG (CH) | 1999-05-12 | — | — | CN | disclosed |