Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27379299 | 0.81 | HDAC4 (0.36) | MEN1KMT2AATMGRM6HDAC4 | |
| SCHEMBL30755433 | 0.81 | HDAC4 (0.36) | MEN1KMT2AATMGRM6HDAC4 | |
| SCHEMBL27379394 | 0.80 | HSD11B1 (0.39) | MEN1KMT2AATMNR3C2POLB | |
| SCHEMBL27378973 | 0.79 | MEN1 (0.38) | MEN1KMT2AATMGRM6HDAC4 | |
| SCHEMBL30755472 | 0.79 | IDH1 (0.35) | MEN1KMT2AATMGRM6CYP2C9 | |
| SCHEMBL27375885 | 0.74 | CA12 (0.37) | MEN1KMT2AATM | |
| SCHEMBL27375857 | 0.74 | MEN1 (0.36) | MEN1KMT2AATMHDAC4 | |
| SCHEMBL30755212 | 0.74 | CA12 (0.37) | MEN1KMT2AATM | |
| SCHEMBL27374381 | 0.72 | MEN1 (0.35) | MEN1KMT2AATMCYP2C9CYP2C19 | |
| SCHEMBL27379229 | 0.71 | PARP1 (0.33) | GRM6PLATALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |