Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 6/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27379299 | 1.00 | HDAC4 (0.36) | HDAC4OPRL1MEN1KMT2AATM | |
| SCHEMBL27379394 | 0.87 | HSD11B1 (0.39) | MEN1KMT2AATMNR3C2POLB | |
| SCHEMBL30755472 | 0.86 | IDH1 (0.35) | MEN1KMT2AATMGRM6TP53 | |
| SCHEMBL27377777 | 0.85 | GPR119 (0.36) | SCN5ASCN9AIDH1IDH2GPR119 | |
| SCHEMBL30755349 | 0.85 | GPR119 (0.36) | SCN5ASCN9AIDH1IDH2GPR119 | |
| SCHEMBL27378973 | 0.84 | MEN1 (0.38) | HDAC4MEN1KMT2AATMALDH1A1 | |
| SCHEMBL27375374 | 0.84 | ALOX5AP (0.31) | SCN5ASCN9AIDH1IDH2GPR119 | |
| SCHEMBL30755212 | 0.81 | CA12 (0.37) | MEN1KMT2AATMIDH1IDH2 | |
| SCHEMBL27375885 | 0.81 | CA12 (0.37) | MEN1KMT2AATMIDH1IDH2 | |
| SCHEMBL27375857 | 0.81 | MEN1 (0.36) | HDAC4MEN1KMT2AATMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562016-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |