Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | IL1B | P01584 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30755433 | 0.86 | HDAC4 (0.36) | IDH1IDH2TP53MEN1KMT2A | |
| SCHEMBL27379299 | 0.86 | HDAC4 (0.36) | IDH1IDH2TP53MEN1KMT2A | |
| SCHEMBL30755526 | 0.85 | NR1H2 (0.34) | IDH1IDH2NR1H2NR1H3RXRA | |
| SCHEMBL27379106 | 0.85 | NR1H2 (0.34) | IDH1IDH2NR1H2NR1H3RXRA | |
| SCHEMBL27379394 | 0.85 | HSD11B1 (0.39) | TP53MEN1KMT2AATMIL1B | |
| SCHEMBL27378973 | 0.82 | MEN1 (0.38) | IDH1IDH2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30755212 | 0.80 | CA12 (0.37) | IDH1IDH2MEN1KMT2AATM | |
| SCHEMBL27375857 | 0.80 | MEN1 (0.36) | IDH1IDH2NR1H2TP53MEN1 | |
| SCHEMBL27375885 | 0.80 | CA12 (0.37) | IDH1IDH2MEN1KMT2AATM | |
| SCHEMBL27379265 | 0.79 | MEN1 (0.33) | CYP2C9CYP2C19MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562016-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |