SCHEMBL27379394

SCHEMBL27379394

Cc1c(Cl)ccc(C2CCC(F)(F)CC2)c1C(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 1/20 0.39
▸ NR3C2 P08235 1/20 0.36
▸ IL1B P01584 4/20 0.35
▸ P2RX7 Q99572 4/20 0.35
▸ RORC P51449 6/20 0.34
▸ TSHR P16473 1/20 0.34
▸ TP53 P04637 3/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ SCN10A Q9Y5Y9 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27379299 0.87 HDAC4 (0.36) NR3C2TP53POLBMEN1KMT2A
SCHEMBL30755433 0.87 HDAC4 (0.36) NR3C2TP53POLBMEN1KMT2A
SCHEMBL30755381 0.85 P2RX7 (0.35) HSD11B1NR3C2IL1BP2RX7RORC
SCHEMBL27379422 0.85 P2RX7 (0.35) HSD11B1NR3C2IL1BP2RX7RORC
SCHEMBL30755472 0.85 IDH1 (0.35) HSD11B1IL1BP2RX7TP53SCN10A
SCHEMBL27378973 0.83 MEN1 (0.38) IL1BP2RX7MEN1KMT2AATM
SCHEMBL27375857 0.81 MEN1 (0.36) IL1BP2RX7RORCTP53MEN1
SCHEMBL27375885 0.81 CA12 (0.37) HSD11B1IL1BP2RX7RORCMEN1
SCHEMBL30755212 0.81 CA12 (0.37) HSD11B1IL1BP2RX7RORCMEN1
SCHEMBL27379265 0.80 MEN1 (0.33) NR3C2POLBMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS INC (US) 2026-02-05 — — US disclosed
EP-4562016-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 — — EP disclosed
WO-2024026483-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 — — WO disclosed
WO-2024026483-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CDK2, CDK1, CDK20 HSD11B1 818/4885NR3C2 60/4885IL1B 4842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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