Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27380712 | 0.90 | MCHR1 (0.40) | EPHX2ENPP2FPR2WRNMAPT | |
| SCHEMBL27377081 | 0.89 | FPR2 (0.41) | EPHX2ENPP2FPR2WRNLMNA | |
| SCHEMBL27377219 | 0.89 | EPHX2 (0.40) | EPHX2ENPP2FPR2WRNLMNA | |
| SCHEMBL27381048 | 0.88 | EPHX2 (0.38) | EPHX2ENPP2FPR2WRNLMNA | |
| SCHEMBL27380972 | 0.87 | ENPP2 (0.39) | EPHX2ENPP2FPR2WRNLMNA | |
| SCHEMBL27381330 | 0.87 | PDE2A (0.37) | EPHX2ENPP2FPR2WRNLMNA | |
| SCHEMBL31005804 | 0.86 | KDM4E (0.39) | EPHX2ENPP2FPR2WRNLMNA | |
| SCHEMBL27380776 | 0.85 | MCHR1 (0.37) | EPHX2ENPP2FPR2WRNLMNA | |
| SCHEMBL27381045 | 0.84 | WRN (0.38) | EPHX2ENPP2FPR2WRNLMNA | |
| SCHEMBL27380969 | 0.84 | WRN (0.36) | EPHX2ENPP2FPR2WRNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105553-A1 | BICYCLIC HETEROCYCLES AND THEIR USE AS WRN INHIBITORS | NOVARTIS AG (CH) | 2024-05-23 | — | — | WO | disclosed |