Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.65 |
| ▸ | TP53 | P04637 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27383551 | 0.86 | MAPT (0.56) | MAPTTP53POLBPTGER3LMNA | |
| SCHEMBL30799051 | 0.84 | CNR1 (0.51) | MAPTTP53POLBPTGER3LMNA | |
| SCHEMBL16199218 | 0.84 | LMNA (0.70) | MAPTTP53POLBPTGER3LMNA | |
| SCHEMBL14324139 | 0.83 | LMNA (0.57) | MAPTTP53POLBPTGER3LMNA | |
| SCHEMBL27383780 | 0.82 | MAPT (0.68) | MAPTTP53POLBPTGER3LMNA | |
| SCHEMBL28223471 | 0.81 | MAPT (0.62) | MAPTTP53POLBPTGER3LMNA | |
| SCHEMBL7261844 | 0.80 | ABHD6 (0.52) | MAPTPOLBPTGER3LMNA | |
| SCHEMBL27383538 | 0.80 | LMNA (0.58) | MAPTTP53PTGER3LMNA | |
| SCHEMBL20995404 | 0.79 | EGLN1 (0.69) | MAPTTP53POLBPTGER3LMNA | |
| SCHEMBL27383531 | 0.79 | MAPT (0.61) | MAPTTP53POLBPTGER3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050825-A1 | COMPOUNDS AS MLKL INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2024-03-14 | — | — | WO | disclosed |