Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27384456 | 0.90 | RAB9A (0.37) | AADATRAB9ASMN1; SMN2POLBHRH3 | |
| SCHEMBL27384854 | 0.83 | MAPK1 (0.41) | RAB9AALDH1A1SMN1; SMN2POLBHRH3 | |
| SCHEMBL27384346 | 0.82 | EIF4A3 (0.45) | AADATRAB9AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL27383269 | 0.79 | RAB9A (0.56) | RAB9AHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL27384455 | 0.79 | RAB9A (0.41) | RAB9AHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL27385164 | 0.78 | RAB9A (0.41) | RAB9ASMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL27384349 | 0.78 | SMN1; SMN2 (0.38) | RAB9ASMN1; SMN2HRH3MAPK1 | |
| SCHEMBL27385039 | 0.78 | RAB9A (0.42) | RAB9AHPGDALDH1A1SMN1; SMN2MTNR1A | |
| SCHEMBL27384178 | 0.77 | SMN1; SMN2 (0.42) | RAB9AHPGDSMN1; SMN2POLBSSTR3 | |
| SCHEMBL27385399 | 0.77 | PKM (0.47) | RAB9AHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |