Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27384451 | 0.90 | AADAT (0.38) | RAB9AAADATSMN1; SMN2HRH3MAPK1 | |
| SCHEMBL27384854 | 0.83 | MAPK1 (0.41) | RAB9ASMN1; SMN2HRH3MAPK1POLB | |
| SCHEMBL27383269 | 0.79 | RAB9A (0.56) | RAB9ASMN1; SMN2MTNR1AMTNR1BPOLB | |
| SCHEMBL27385164 | 0.78 | RAB9A (0.41) | RAB9ASMN1; SMN2MTNR1AMTNR1BMEN1 | |
| SCHEMBL27384349 | 0.78 | SMN1; SMN2 (0.38) | RAB9ASMN1; SMN2HRH3MAPK1EPHX2 | |
| SCHEMBL27385039 | 0.78 | RAB9A (0.42) | RAB9ASMN1; SMN2MTNR1AMTNR1BMEN1 | |
| SCHEMBL27384178 | 0.77 | SMN1; SMN2 (0.42) | RAB9ASMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL27385036 | 0.76 | RAB9A (0.43) | RAB9ASMN1; SMN2MTNR1AMTNR1BMEN1 | |
| SCHEMBL27385903 | 0.76 | SMN1; SMN2 (0.50) | RAB9ASMN1; SMN2MAPK1MTNR1AMTNR1B | |
| SCHEMBL27382675 | 0.75 | MTNR1A (0.44) | RAB9ASMN1; SMN2MTNR1AMTNR1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |