Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 2/20 | 0.38 |
| ▸ | SELE | P16581 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 4/20 | 0.37 |
| ▸ | NNMT | P40261 | 3/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27386940 | 0.82 | NPC1 (0.44) | ATMSIRT2SIRT1SIRT3BACE1 | |
| SCHEMBL13363453 | 0.78 | LMNA (0.38) | ICAM1SELEKCNH2ATMNNMT | |
| SCHEMBL31220981 | 0.75 | KDM4E (0.41) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL2389957 | 0.75 | KDM4E (0.41) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL2338977 | 0.73 | KDM5A (0.40) | CYP11B2KDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL8758676 | 0.72 | KDM5A (0.38) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL13370901 | 0.72 | KDM4E (0.39) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL29619773 | 0.72 | KDM5A (0.38) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL1503252 | 0.72 | HPGDS (0.42) | NNMTSIRT2SIRT1SIRT3SYK | |
| SCHEMBL20180706 | 0.72 | CNR2 (0.38) | KCNH2ATMBACE1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1319599-A | Process for preparing imidazolinone | AMERICAN CYANAMID CO (US) | 2001-10-31 | — | — | CN | disclosed |
| CN-1068882-C | Process for producing 5- (alkoxymethyl) -2, 3-pyridinedicarboximide compound | AMERICAN CYANAMID CO (US) | 2001-07-25 | — | — | CN | disclosed |
| CN-1169995-A | Process for producing 5- (alkoxymethyl) -2, 3-pyridinedicarboximide compound | AMERICAN CYANAMID CO (US) | 1998-01-14 | — | — | CN | disclosed |